TY - JOUR T1 - Tumor Index as a Combined Indicator of Tumor Depth and Size in Gastric Cancer JF - Anticancer Research JO - Anticancer Res SP - 1895 LP - 1900 VL - 36 IS - 4 AU - TAKUMA OHASHI AU - SHUHEI KOMATSU AU - DAISUKE ICHIKAWA AU - TOSHIYUKI KOSUGA AU - KAZUMA OKAMOTO AU - HIROTAKA KONISHI AU - ATSUSHI SHIOZAKI AU - HITOSHI FUJIWARA AU - EIGO OTSUJI Y1 - 2016/04/01 UR - http://ar.iiarjournals.org/content/36/4/1895.abstract N2 - Background: We investigated the utility of a novel combined indicator of both tumor depth and size in gastric cancer. Patients and Methods: A total of 938 patients with gastric cancer were analyzed. We tested tumor index (TI), calculated by T category × tumor size (mm) as a novel combined indicator of tumor depth and size. Results: Patients were classified into two groups using a cut-off value of 180 (p<0.0001) by the Kaplan–Meier method. TI was significantly positively correlated with older age, tumor located in the upper third of stomach, advanced type of macroscopic appearance, undifferentiated type, lymphatic invasion, venous invasion, lymph node metastasis, and recurrence. TI>180 only correlated with peritoneal recurrence (p=0.0394). A multivariate analysis identified TI>180 as an independent prognostic factor (hazard ratio=2.38, p=0.0004). Conclusion: TI may be a novel combined indicator of tumor status for predicting a poor prognosis and peritoneal recurrence in gastric cancer. ER -