PT - JOURNAL ARTICLE AU - KATHARINA MARSONER AU - PETER KORNPRAT AU - GOTTFRIED SODECK AU - JAKOB SCHAGERL AU - RAINER LANGEDER AU - DORA CSENGERI AU - DORIS WAGNER AU - HANS JOERG MISCHINGER AU - JOHANNES HAYBAECK TI - Pancreas Cancer Surgery in Octogenarians – Should We or Should We Not? DP - 2016 Apr 01 TA - Anticancer Research PG - 1979--1984 VI - 36 IP - 4 4099 - http://ar.iiarjournals.org/content/36/4/1979.short 4100 - http://ar.iiarjournals.org/content/36/4/1979.full SO - Anticancer Res2016 Apr 01; 36 AB - Background/Aim: In this study we aimed to determine if advanced age represents a risk factor for negative perioperative and long-term outcome in patients undergoing curative surgery ductal pancreatic adenocarcinoma surgery. Patients and Methods: Two-hundred-twenty-one consecutive patients, twelve (6%) patients ≥80 years were included in the study. We assessed perioperative and long-term outcome and independent predictors for in-hospital mortality with Cox regression analysis. Results: Advanced age was not a predictor for in-hospital mortality (6.3% in non-octogenarian versus 8.3% in octogenarians; p=0.55) nor for morbidity (31% vs. 32%; p=0.69). An ASA score >II was the only predictor for in-hospital mortality (odds ratio (OR)=10.10, 95%CI=1.28-79.60; Hosmer-Lemeshow: p=0.86). No significant difference was observed in one- and five-year survival rates (68 and 58% vs. 16 and 14%; log-rank p=0.61). Conclusion: Advanced age is not a risk factor for negative outcome in curative pancreatic cancer surgery. Therefore, this single curative option should be considered in octogenarians at risk.