RT Journal Article
SR Electronic
T1 A Survival Score for Patients Receiving Stereotactic Radiosurgery Alone for Brain Metastases from Breast Cancer
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 1073
OP 1076
VO 36
IS 3
A1 RADES, DIRK
A1 DZIGGEL, LIESA
A1 JANSSEN, STEFAN
A1 BLANCK, OLIVER
A1 HORNUNG, DAGMAR
A1 SCHILD, STEVEN E.
YR 2016
UL http://ar.iiarjournals.org/content/36/3/1073.abstract
AB Aim: To generate a survival score for patients with breast cancer treated with stereotactic radiosurgery (SRS) alone for brain metastases. Patients and Methods: Seven factors were evaluated in 34 patients, namely age, performance score, number of brain metastases, maximum diameter of all brain metastases, location of brain metastases, extracerebral metastases and time between breast cancer diagnosis and SRS. The score was created from factors having a significant impact on survival. Points of 0 (worse survival) or 1 (better survival) were assigned. Factor scores were added to total prognostic scores for each patient. Results: A significant impact on survival was found for performance score (p<0.001), maximum diameter of cerebral lesions (p=0.002), and extracerebral metastases (p=0.026). Three groups were designated by score: 0-1, 2 and 3 points. One-year survival rates were 48%, 71% and 100%, respectively (p<0.001). Conclusion: This score contributes to appropriate selection of personalized treatment in patients with breast cancer with few cerebral metastases.