TY - JOUR T1 - Hypocalcaemia After Total Knee Arthroplasty and its Clinical Significance JF - Anticancer Research JO - Anticancer Res SP - 1309 LP - 1311 VL - 36 IS - 3 AU - PENGZHOU GAI AU - HONGLIANG SUN AU - LAIJIAN SUI AU - GUANGDA WANG Y1 - 2016/03/01 UR - http://ar.iiarjournals.org/content/36/3/1309.abstract N2 - Background: Transient hypocalcaemia is a frequent complication after total knee arthroplasty (TKA). In this study, we investigated the factors associated with the development of hypocalcaemia after TKA in order to explore its clinical significance and treatment. Patients and Methods: A retrospective analysis of the change of serum calcium levels for 40 patients after TKA was performed. We investigated the patients prospectively for age, gender, and amount of bleeding at operation. At 24 hours following the operation, serum calcium of the patients was evaluated and a t-test was performed to analyze the categorical variables. Pearson's correlation analysis was used to determine the risk of hypocalcaemia in univariate analysis. Results: After TKA, the serum calcium level was significantly lower than that before the operation (p<0.01); the incidence of postoperative hypocalcaemia was 77.5%, the decline was positively correlated with intraoperative blood loss (Pearson's r=0.405, p=0.01). Conclusion: Hypocalcaemia occurs frequently after TKA, however, clinical symptoms associated with hypocalcaemia are rare. The calcium ion is an important electrolyte, neurotransmitter and blood coagulation factor. It is suggested that we should routinely monitor calcium ion levels during the perioperative period and deal with hypocalcaemia in a timely fashion. ER -