TY - JOUR T1 - Expression of γ-Synuclein in Bladder Carcinoma: A Possible Marker for Prognosis JF - Anticancer Research JO - Anticancer Res SP - 951 LP - 956 VL - 36 IS - 3 AU - ZHIGANG CHEN AU - ZHIGANG JI AU - QINGHAI WANG AU - BINGBING SHI AU - CHENGCHAO SHOU AU - CAIYUN LIU AU - HUA FAN AU - HANZHONG LI AU - KRISTOFFER T. DAVIDSON AU - MARK R. WAKEFIELD AU - TYLER W. BALL AU - YUJIANG FANG Y1 - 2016/03/01 UR - http://ar.iiarjournals.org/content/36/3/951.abstract N2 - Aim: To investigate if γ-synuclein (SNCG) could be used as a bladder cancer (BC) marker to predict prognosis of BC. Patients and Methods: Medical records of 140 patients with BC (January, 2006 to December, 2009) were retrospectively reviewed. SNCG expression level was examined by immunohistological staining. The patients' survival rate was calculated by the Kaplan–Meier method. Cox proportional regression model was used to identify independent predictors for BC. Results: Overexpression of SNCG was detected in BC tissues and the expression level of SNCG strongly positively correlated with BC recurrence. However, no correlation was found between SNCG level and tumor stage or survival rate. Conclusion: SNCG is a good marker to predict recurrence of BC, but not a reliable marker for staging or prediction of survival rate. ER -