TY - JOUR T1 - Unresectable Middle Mediastinal Biphasic Pulmonary Blastoma JF - Anticancer Research JO - Anticancer Res SP - 6325 LP - 6327 VL - 35 IS - 11 AU - KELSEY GALLO AU - ARLEN BRICKMAN AU - WILLIAM H. WARREN AU - PAOLO GATTUSO AU - CHRISTOPHER W. SEDER Y1 - 2015/11/01 UR - http://ar.iiarjournals.org/content/35/11/6325.abstract N2 - We report a case of a young male who presented with an unresectable, centrally-located classic biphasic pulmonary blastoma (CBPB) involving his bilateral mainstem bronchi and esophagus and a synchronous right testicular seminoma. CBPB is a rare and aggressive tumor that most commonly presents as a solitary mass in the periphery of the lung. Surgical resection is the preferred treatment for CBPB, as chemotherapy and radiation have demonstrated limited effectiveness. In the current case, four cycles of cisplatin, ifosfamide, and etoposide with concurrent radiotherapy resulted in a favorable response at three months. Currently he optimal treatment for unresectable pulmonary blastomas remains undefined. ER -