PT - JOURNAL ARTICLE AU - KELSEY GALLO AU - ARLEN BRICKMAN AU - WILLIAM H. WARREN AU - PAOLO GATTUSO AU - CHRISTOPHER W. SEDER TI - Unresectable Middle Mediastinal Biphasic Pulmonary Blastoma DP - 2015 Nov 01 TA - Anticancer Research PG - 6325--6327 VI - 35 IP - 11 4099 - http://ar.iiarjournals.org/content/35/11/6325.short 4100 - http://ar.iiarjournals.org/content/35/11/6325.full SO - Anticancer Res2015 Nov 01; 35 AB - We report a case of a young male who presented with an unresectable, centrally-located classic biphasic pulmonary blastoma (CBPB) involving his bilateral mainstem bronchi and esophagus and a synchronous right testicular seminoma. CBPB is a rare and aggressive tumor that most commonly presents as a solitary mass in the periphery of the lung. Surgical resection is the preferred treatment for CBPB, as chemotherapy and radiation have demonstrated limited effectiveness. In the current case, four cycles of cisplatin, ifosfamide, and etoposide with concurrent radiotherapy resulted in a favorable response at three months. Currently he optimal treatment for unresectable pulmonary blastomas remains undefined.