PT  - JOURNAL ARTICLE
AU  - RADES, DIRK
AU  - DAHLKE, MARKUS
AU  - GEBAUER, NIKLAS
AU  - BARTSCHT, TOBIAS
AU  - HORNUNG, DAGMAR
AU  - TRANG, NGO THUY
AU  - PHUONG, PHAM CAM
AU  - KHOA, MAI TRONG
AU  - GLIEMROTH, JAN
TI  - A New Predictive Tool for Optimization of the Treatment of Brain Metastases from Colorectal Cancer After Stereotactic Radiosurgery
DP  - 2015 Oct 01
TA  - Anticancer Research
PG  - 5515--5518
VI  - 35
IP  - 10
4099  - http://ar.iiarjournals.org/content/35/10/5515.short
4100  - http://ar.iiarjournals.org/content/35/10/5515.full
SO  - Anticancer Res2015 Oct 01; 35
AB  - Aim: To develop a predictive tool for survival after stereotactic radiosurgery of brain metastases from colorectal cancer. Patients and Methods: Out of nine factors analyzed for survival, those showing significance (p<0.05) or a trend (p≤0.06) were included. For each factor, 0 (worse survival) or 1 (better survival) point was assigned. Total scores represented the sum of the factor scores. Results: Performance status (p=0.010) and interval from diagnosis of colorectal cancer until radiosurgery (p=0.026) achieved significance, extracranial metastases showed a trend (p=0.06). These factors were included in the tool. Total scores were 0-3 points. Six-month survival rates were 17% for patients with 0, 25% for those with 1, 67% for those with 2 and 100% for those with 3 points; 12-month rates were 0%, 0%, 33% and 67%, respectively. Two groups were created: 0-1 and 2-3 points. Six- and 12-month survival rates were 20% vs. 78% and 0% vs. 44% (p=0.002), respectively. Conclusion: This tool helps optimize the treatment of patients after stereotactic radiosurgery for brain metastases from colorectal cancer.