RT Journal Article SR Electronic T1 Oral Colostrum Macrophage-activating Factor for Serious Infection and Chronic Fatigue Syndrome: Three Case Reports JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 4545 OP 4549 VO 35 IS 8 A1 TOSHIO INUI A1 KENTARO KUBO A1 DAISUKE KUCHIIKE A1 YOSHIHIRO UTO A1 TAKAHITO NISHIKATA A1 NORIHIRO SAKAMOTO A1 MARTIN METTE YR 2015 UL http://ar.iiarjournals.org/content/35/8/4545.abstract AB Background: Gc protein-derived macrophage-activating factor (GcMAF) immunotherapy has been steadily advancing over the last two decades. Oral colostrum macrophage-activating factor (MAF) produced from bovine colostrum has shown high macrophage phagocytic activity. GcMAF-based immunotherapy has a wide application for use in treating many diseases via macrophage activation or for use as supportive therapy. Results: Three case studies demonstrate that oral colostrum MAF can be used for serious infection and chronic fatigue syndrome (CFS) without adverse effects. Conclusion: We demonstrate that colostrum MAF shows promising clinical results in patients with infectious diseases and for symptoms of fatigue, which is common in many chronic diseases.