PT - JOURNAL ARTICLE AU - TOSHIO INUI AU - KENTARO KUBO AU - DAISUKE KUCHIIKE AU - YOSHIHIRO UTO AU - TAKAHITO NISHIKATA AU - NORIHIRO SAKAMOTO AU - MARTIN METTE TI - Oral Colostrum Macrophage-activating Factor for Serious Infection and Chronic Fatigue Syndrome: Three Case Reports DP - 2015 Aug 01 TA - Anticancer Research PG - 4545--4549 VI - 35 IP - 8 4099 - http://ar.iiarjournals.org/content/35/8/4545.short 4100 - http://ar.iiarjournals.org/content/35/8/4545.full SO - Anticancer Res2015 Aug 01; 35 AB - Background: Gc protein-derived macrophage-activating factor (GcMAF) immunotherapy has been steadily advancing over the last two decades. Oral colostrum macrophage-activating factor (MAF) produced from bovine colostrum has shown high macrophage phagocytic activity. GcMAF-based immunotherapy has a wide application for use in treating many diseases via macrophage activation or for use as supportive therapy. Results: Three case studies demonstrate that oral colostrum MAF can be used for serious infection and chronic fatigue syndrome (CFS) without adverse effects. Conclusion: We demonstrate that colostrum MAF shows promising clinical results in patients with infectious diseases and for symptoms of fatigue, which is common in many chronic diseases.