@article {BOLM4105, author = {LOUISA BOLM and STEFAN JANSSEN and LUKAS K{\"A}SMANN and ULRICH WELLNER and TOBIAS BARTSCHT and STEVEN E. SCHILD and DIRK RADES}, title = {Predicting Survival After Irradiation of Metastases from Pancreatic Cancer}, volume = {35}, number = {7}, pages = {4105--4108}, year = {2015}, publisher = {International Institute of Anticancer Research}, abstract = {Background/Aim: Patients with metastases from pancreas cancer benefit from individualized care, including radiotherapy for symptom control. To administer the optimal radiation therapy, it is important to understand a patient{\textquoteright}s prognosis. Patients and Methods: Seven variables were analyzed regarding their relationship with survival: age, gender, Karnofsky performance score (KPS), number of metastatic sites, interval from diagnosis of pancreatic cancer to irradiation of metastases, type of irradiated metastasis, and radiation dose. Results: On univariate analysis, survival was positively associated with age <=67 years (p=0.045), KPS \>70 (p\<0.001), and involvement of only one metastatic site (p=0.013). A longer interval between diagnosis and irradiation of metastases showed a trend for better survival (p=0.077). On multivariate analysis, age [risk ratio (RR)=4.29; p=0.004], KPS (RR=1.95; p=0.020), number of metastatic sites (RR=2.20; p=0.009) and interval to irradiation (RR=4.41; p=0.005) achieved significance. Conclusion: The present study identified four independent predictors of survival in patients with pancreatic cancer irradiated for metastasis and thus contributes to treatment optimization.}, issn = {0250-7005}, URL = {https://ar.iiarjournals.org/content/35/7/4105}, eprint = {https://ar.iiarjournals.org/content/35/7/4105.full.pdf}, journal = {Anticancer Research} }