TY - JOUR T1 - Gastric Cancer Patients with End-stage Renal Disease Who Underwent Radical Gastrectomy JF - Anticancer Research JO - Anticancer Res SP - 2263 LP - 2268 VL - 35 IS - 4 AU - YU-YIN LIU AU - CHUN-YI TSAI AU - CHUN-NAN YEH AU - KUN-CHUN CHIANG AU - SHANG-YU WANG AU - CHI-TUNG CHENG AU - CHIEN-HUNG LIAO AU - JU-TE HSU AU - TA-SEN YEH AU - YI-YIN JAN AU - MIIN-FU CHEN Y1 - 2015/04/01 UR - http://ar.iiarjournals.org/content/35/4/2263.abstract N2 - Background: Radical gastrectomy (RG) with lymph node (LN) dissection is a standard procedure for gastric cancer (GC). Patients with end-stage renal disease (ESRD) usually have high risk for any operative procedure. However, information for ESRD on RG for GC is limited. Patients and Methods: A total of 2,021 GC patients who underwent RG with LN dissection were retrospectively reviewed. Among them, 26 patients had ESRD. The clinicopathological features and surgical outcomes were compared between GC with ESRD (ESRD-GC group) and GC without ESRD (GC group). Results: ESRD-GC patients could be independently differentiated from GC patients by lower hemoglobin, negative lymph node (LN) involvement and higher postoperative complications. The overall survival rate of ESRD-GC group seemed better than that of GC group patients. Lesser depth of tumor invasion, LN metastasis and lymphatic invasion and early-staged tumor contributed to favorable prognosis of ESRD-GC group of patients. Conclusion: RG might be beneficial for GC-ESRD patients especially for early-stage disease; however, RG for GC patients with ESRD should be more cautiously performed, otherwise the benefit might be compromised by higher postoperative compli cations and even mortality. ER -