TY - JOUR T1 - Additional Surgery After Non-curative Resection of ESD for Early Gastric Cancer JF - Anticancer Research JO - Anticancer Res SP - 2969 LP - 2974 VL - 35 IS - 5 AU - TAKAO KATSUBE AU - MINORU MURAYAMA AU - KENTARO YAMAGUCHI AU - ATSUKO USUDA AU - ASAKO SHIMAZAKI AU - SHINICHI ASAKA AU - SOICH KONNNO AU - AKIRA MIYAKI AU - TAKEBUMI USUI AU - HAZIME YOKOMIZO AU - SCHUNICHI SHIOZAWA AU - KAZUHIKO YOSHIMATSU AU - TAKESHI SHIMAKAWA AU - YOSHIHIKO NARITAKA Y1 - 2015/05/01 UR - http://ar.iiarjournals.org/content/35/5/2969.abstract N2 - Aim: The appropriate additional surgery after non-curative resection of Endoscopic Mucosal Resection (ESD) for early gastric cancer is herein discussed. Patients and Methods: Data on 54 patients after non-curative resection of ESD were evaluated. These patients were broadly classified according to the risk of lymph node metastasis with lesions into group A (without risk) (n=26) and group B (with risk) (n=28). Their treatment results were evaluated. Results: The incidence of residual lesion was 7.7% in group A and 14.3% in group B. Risk factors were piecemeal resection, involvement of the horizontal margin (HM1) or unclear involvement of the horizontal margin (HMX) and with ulceration. Lymph node metastasis was detected in one patient with lymphatic invasion, total diameter of 3 cm or more and submucosal invasion over 0.5 mm (SM2). The 5-year survival rate was 93% and none of the patients died of gastric cancer. Conclusion: Follow-up observation was reasonable in group A. Patients who are judged as having undergone piecemeal resection, HM1 or HMX and with ulceration, should be treated by additional surgery and patients judged with SM2 or total diameter of 3 cm or more or lymphatic invasion should be treated by additional surgery with lymphadectomy in groupB. ER -