<?xml version='1.0' encoding='UTF-8'?><xml><records><record><source-app name="HighWire" version="7.x">Drupal-HighWire</source-app><ref-type name="Journal Article">17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">IGUCHI, TOMOHIRO</style></author><author><style face="normal" font="default" size="100%">UCHI, RYUTARO</style></author><author><style face="normal" font="default" size="100%">NAMBARA, SHO</style></author><author><style face="normal" font="default" size="100%">SAITO, TOMOKO</style></author><author><style face="normal" font="default" size="100%">KOMATSU, HISATERU</style></author><author><style face="normal" font="default" size="100%">HIRATA, HIDENARI</style></author><author><style face="normal" font="default" size="100%">UEDA, MASAMI</style></author><author><style face="normal" font="default" size="100%">SAKIMURA, SHOTARO</style></author><author><style face="normal" font="default" size="100%">TAKANO, YUKI</style></author><author><style face="normal" font="default" size="100%">KURASHIGE, JYUNJI</style></author><author><style face="normal" font="default" size="100%">SHINDEN, YOSHIAKI</style></author><author><style face="normal" font="default" size="100%">EGUCHI, HIDETOSHI</style></author><author><style face="normal" font="default" size="100%">SUGIMACHI, KEISHI</style></author><author><style face="normal" font="default" size="100%">MAEHARA, YOSHIHIKO</style></author><author><style face="normal" font="default" size="100%">MIMORI, KOSHI</style></author></authors><secondary-authors></secondary-authors></contributors><titles><title><style face="normal" font="default" size="100%">A Long Noncoding RNA, lncRNA-ATB, Is Involved in the Progression and Prognosis of Colorectal Cancer</style></title><secondary-title><style face="normal" font="default" size="100%">Anticancer Research</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2015-03-01 00:00:00</style></date></pub-dates></dates><pages><style  face="normal" font="default" size="100%">1385-1388</style></pages><volume><style face="normal" font="default" size="100%">35</style></volume><issue><style face="normal" font="default" size="100%">3</style></issue><abstract><style  face="normal" font="default" size="100%">Background/Aim: A long noncoding RNA (lncRNA) activated by transforming growth factor (TGF)-β (lncRNA-ATB) was recently described to promote the invasion-metastasis cascade in hepatocellular carcinoma. The aim of the present study was to clarify the clinicopathological role and prognostic relevance of lncRNA-ATB in colorectal cancer (CRC). Materials and Methods: lncRNA-ATB expression was evaluated by real-time reverse transcription polymerase chain reaction in 124 patients with CRC. Patients were divided into two groups based on the median lncRNA-ATB expression. Results: High lncRNA-ATB expression was significantly associated with greater tumor size, depth of tumor invasion, lymphatic invasion, vascular invasion, and lymph node metastasis. Patients of the high-lncRNA-ATB expression group had significantly poorer outcomes than those of the low-expression group. Additionally, levels of lncRNA-ATB expression were significantly higher in patients with hematogenous metastases. Conclusion: lncRNA-ATB may be involved in the progression of CRC and be a novel indicator of poor prognosis in patients with CRC.</style></abstract></record></records></xml>