RT Journal Article
SR Electronic
T1 Salvage Method for Unplanned Excision of Soft Tissue Sarcoma: Long-term Results of Second-look Surgery Following Radio-hyperthermo-chemotherapy
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 493
OP 498
VO 35
IS 1
A1 KATSUHIRO HAYASHI
A1 SATOSHI YAMADA
A1 HIROYUKI INATANI
A1 HIDEKI OKAMOTO
A1 AKIHIKO TAKEUCHI
A1 HIDEJI NISHIDA
A1 NORIO YAMAMOTO
A1 HIROYUKI TSUCHIYA
A1 TAKANOBU OTSUKA
YR 2015
UL http://ar.iiarjournals.org/content/35/1/493.abstract
AB We have established a “second-look operation” protocol that consists of whole biopsy of surgical scar tissue following radio-hyperthermo-chemotherapy (RHC) after unplanned excision of soft tissue sarcoma. Out of 30 patients who underwent RHC for soft tissue sarcoma at our Institution, 6 were enrolled into this study to undergo a second-look operation for unplanned excision. Radiotherapy was given to a total dose of 32 Gy. Hyperthermia was conducted once a week, for a total of five sessions. Chemotherapy was performed at weekly intervals. Surgery was performed to excise the scar tissue that was enhanced on preoperative MRI. In all six cases, no residual tumors were identified in resected scar tissue; thus, no additional wide excision was performed. The average follow-up period was 10.9 years. There were no local recurrences, and all patients were alive at their final follow-up. Long-term follow-up confirmed that RHC can replace additional wide excision for unplanned excision of soft tissue sarcoma.