PT  - JOURNAL ARTICLE
AU  - KATSUHIRO HAYASHI
AU  - SATOSHI YAMADA
AU  - HIROYUKI INATANI
AU  - HIDEKI OKAMOTO
AU  - AKIHIKO TAKEUCHI
AU  - HIDEJI NISHIDA
AU  - NORIO YAMAMOTO
AU  - HIROYUKI TSUCHIYA
AU  - TAKANOBU OTSUKA
TI  - Salvage Method for Unplanned Excision of Soft Tissue Sarcoma: Long-term Results of Second-look Surgery Following Radio-hyperthermo-chemotherapy
DP  - 2015 Jan 01
TA  - Anticancer Research
PG  - 493--498
VI  - 35
IP  - 1
4099  - http://ar.iiarjournals.org/content/35/1/493.short
4100  - http://ar.iiarjournals.org/content/35/1/493.full
SO  - Anticancer Res2015 Jan 01; 35
AB  - We have established a “second-look operation” protocol that consists of whole biopsy of surgical scar tissue following radio-hyperthermo-chemotherapy (RHC) after unplanned excision of soft tissue sarcoma. Out of 30 patients who underwent RHC for soft tissue sarcoma at our Institution, 6 were enrolled into this study to undergo a second-look operation for unplanned excision. Radiotherapy was given to a total dose of 32 Gy. Hyperthermia was conducted once a week, for a total of five sessions. Chemotherapy was performed at weekly intervals. Surgery was performed to excise the scar tissue that was enhanced on preoperative MRI. In all six cases, no residual tumors were identified in resected scar tissue; thus, no additional wide excision was performed. The average follow-up period was 10.9 years. There were no local recurrences, and all patients were alive at their final follow-up. Long-term follow-up confirmed that RHC can replace additional wide excision for unplanned excision of soft tissue sarcoma.