RT Journal Article
SR Electronic
T1 Primary Gastric Small Cell Carcinoma: A Series of Seven Cases
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 563
OP 567
VO 35
IS 1
A1 TAKAHIRO TOYOKAWA
A1 HIROAKI TANAKA
A1 KAZUYA MUGURUMA
A1 TATSURO TAMURA
A1 KATSUNOBU SAKURAI
A1 NAOSHI KUBO
A1 MASAICHI OHIRA
A1 KOSEI HIRAKAWA
YR 2015
UL http://ar.iiarjournals.org/content/35/1/563.abstract
AB Aim: To present a series of seven cases of gastric small cell carcinoma (GSCC) treated surgically and to illustrate the clinicopathological features and clinical course. Patients and Methods: Among 1,832 patients with gastric cancer who underwent gastric resection between 1997 and 2012, we reviewed the clinical records of 7 patients with histopathological diagnoses of GSCC. Results: No patients had preoperative confirmation of GSCC from endoscopic biopsy. Curative resection (R0) was achieved in 5 patients (71.4%). Two out of the 5 patients with curative resection survived more than four years. Two out of 3 patients who received weekly paclitaxel had progression-free survival of more than 10 months. The median survival time for the whole patient group was 14 months and the 3-year survival rate was 25.0%. Conclusion: Curative surgery with adjuvant chemotherapy may be essential to improve the prognosis of GSCC, and weekly paclitaxel chemotherapy may represent a promising chemotherapy for GSCC.