TY - JOUR T1 - Vitamin D Levels and Dietary Intake Among Patients with Benign Soft Tissue Tumors and Sarcomas JF - Anticancer Research JO - Anticancer Res SP - 1171 LP - 1180 VL - 35 IS - 2 AU - ASTA JUZENIENE AU - ALINA CARMEN POROJNICU AU - ZIVILE BATURAITE AU - ZOYA LAGUNOVA AU - LAGE AKSNES AU - ØYVIND SVERRE BRULAND AU - JOHAN MOAN Y1 - 2015/02/01 UR - http://ar.iiarjournals.org/content/35/2/1171.abstract N2 - Background: Calcitriol [1,25(OH)2D] is hypothesized to lower the risk of cancer via binding to the vitamin D receptor (VDR). VDRs are also found in benign and malignant cells of mesenchymal origin. To our knowledge, vitamin D levels and dietary intake have not been previously evaluated in patients newly diagnosed with benign and malignant mesenchymal tumors. Patients and Methods: Forty-eight patients with benign soft tissue tumors and 25 patients with sarcoma had their serum 25-hydroxyvitamin D [25(OH)D], 1,25(OH)2D and parathyroid hormone levels measured, vitamin D intake scored and body mass index [BMI] calculated. Results: Vitamin D deficiency [25(OH)D level <50 nmol/l] was observed in 19% and 28% of patients with benign tumor and sarcoma, respectively. Conclusion: Serum 25(OH)D, 1,25(OH)2D and parathyroid hormone concentrations, BMI and daily vitamin D intake did not differ significantly between the two groups of patients. Higher vitamin D intake or UV exposure is needed to ensure that all patients achieve sufficient vitamin D levels. ER -