PT - JOURNAL ARTICLE AU - ASTA JUZENIENE AU - ALINA CARMEN POROJNICU AU - ZIVILE BATURAITE AU - ZOYA LAGUNOVA AU - LAGE AKSNES AU - ØYVIND SVERRE BRULAND AU - JOHAN MOAN TI - Vitamin D Levels and Dietary Intake Among Patients with Benign Soft Tissue Tumors and Sarcomas DP - 2015 Feb 01 TA - Anticancer Research PG - 1171--1180 VI - 35 IP - 2 4099 - http://ar.iiarjournals.org/content/35/2/1171.short 4100 - http://ar.iiarjournals.org/content/35/2/1171.full SO - Anticancer Res2015 Feb 01; 35 AB - Background: Calcitriol [1,25(OH)2D] is hypothesized to lower the risk of cancer via binding to the vitamin D receptor (VDR). VDRs are also found in benign and malignant cells of mesenchymal origin. To our knowledge, vitamin D levels and dietary intake have not been previously evaluated in patients newly diagnosed with benign and malignant mesenchymal tumors. Patients and Methods: Forty-eight patients with benign soft tissue tumors and 25 patients with sarcoma had their serum 25-hydroxyvitamin D [25(OH)D], 1,25(OH)2D and parathyroid hormone levels measured, vitamin D intake scored and body mass index [BMI] calculated. Results: Vitamin D deficiency [25(OH)D level <50 nmol/l] was observed in 19% and 28% of patients with benign tumor and sarcoma, respectively. Conclusion: Serum 25(OH)D, 1,25(OH)2D and parathyroid hormone concentrations, BMI and daily vitamin D intake did not differ significantly between the two groups of patients. Higher vitamin D intake or UV exposure is needed to ensure that all patients achieve sufficient vitamin D levels.