RT Journal Article
SR Electronic
T1 Multiparametric Pelvic MRI Accuracy in Diagnosing Clinically Significant Prostate Cancer in the Reevaluation of Biopsy Microfocal Tumor
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 395
OP 399
VO 35
IS 1
A1 PIETRO PEPE
A1 GIUSEPPE DIBENEDETTO
A1 ANTONIO GARUFI
A1 GIANDOMENICO PRIOLO
A1 MICHELE PENNISI
YR 2015
UL http://ar.iiarjournals.org/content/35/1/395.abstract
AB Aim: To evaluate the accuracy of multi-parametric pelvic magnetic resonance imaging (mpMRI) in diagnosing prostate cancer (PCa) in men with initial biopsy microfocal cancer. Patients and Methods: From January 2012 to July 2014, 40 patients before undergoing repeat transperineal saturation prostate biopsy (SPBx; median, 28 cores) for the presence of a microfocal PCa were submitted to 3.0-Tesla mpMRI. Results: A T1c clinical stage PCa was found in 23 (57.5%) patients submitted to SPBx; mpMRI was positive in 16/40 (40%) cases and in 11 of them a clinically significant PCa was found. On the contrary, the 12 men with negative mpMRI had a quantitative histology suitable for clinically insignificant cancer. Diagnostic accuracy of mpMRI in diagnosing significant PCa was equal to 100%. Conclusion: Multi-parametric pMRI should be suggested in the re-evaluation of microfocal cancer as a selection approach of patients at risk for clinically significant PCa.