PT  - JOURNAL ARTICLE
AU  - PIETRO PEPE
AU  - GIUSEPPE DIBENEDETTO
AU  - ANTONIO GARUFI
AU  - GIANDOMENICO PRIOLO
AU  - MICHELE PENNISI
TI  - Multiparametric Pelvic MRI Accuracy in Diagnosing Clinically Significant Prostate Cancer in the Reevaluation of Biopsy Microfocal Tumor
DP  - 2015 Jan 01
TA  - Anticancer Research
PG  - 395--399
VI  - 35
IP  - 1
4099  - http://ar.iiarjournals.org/content/35/1/395.short
4100  - http://ar.iiarjournals.org/content/35/1/395.full
SO  - Anticancer Res2015 Jan 01; 35
AB  - Aim: To evaluate the accuracy of multi-parametric pelvic magnetic resonance imaging (mpMRI) in diagnosing prostate cancer (PCa) in men with initial biopsy microfocal cancer. Patients and Methods: From January 2012 to July 2014, 40 patients before undergoing repeat transperineal saturation prostate biopsy (SPBx; median, 28 cores) for the presence of a microfocal PCa were submitted to 3.0-Tesla mpMRI. Results: A T1c clinical stage PCa was found in 23 (57.5%) patients submitted to SPBx; mpMRI was positive in 16/40 (40%) cases and in 11 of them a clinically significant PCa was found. On the contrary, the 12 men with negative mpMRI had a quantitative histology suitable for clinically insignificant cancer. Diagnostic accuracy of mpMRI in diagnosing significant PCa was equal to 100%. Conclusion: Multi-parametric pMRI should be suggested in the re-evaluation of microfocal cancer as a selection approach of patients at risk for clinically significant PCa.