RT Journal Article SR Electronic T1 L-[3-18F]-α-Methyltyrosine Uptake by Lymph Node Metastasis Is a Predictor of Complete Response to CRT in Esophageal Cancer JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 7473 OP 7477 VO 34 IS 12 A1 SOHDA, MAKOTO A1 MIYAZAKI, TATSUYA A1 HONJYO, HIROAKI A1 HARA, KEIGO A1 OZAWA, DAIGO A1 SUZUKI, SHIGEMASA A1 TANAKA, NARITAKA A1 SANO, AKIHIKO A1 SAKAI, MAKOTO A1 YOKOBORI, TAKEHIKO A1 NAKAJIMA, MASANOBU A1 FUKUCHI, MINORU A1 KATO, HIROYUKI A1 HIGUCHI, TETSUYA A1 TSUSHIMA, YOSHITO A1 KUWANO, HIROYUKI YR 2014 UL http://ar.iiarjournals.org/content/34/12/7473.abstract AB Background/Aim: The amino acid positron emission tomography (PET) tracer [18F]-3-fluoro-alpha-methyltyrosine (18F-FAMT) is known to be highly specific for malignancies. We evaluated the accumulation of 18F-FDG or 18F-FAMT in lymph nodes (LN) prior to definitive chemoradiotherapy (CRT) for esophageal cancer. Patients and Methods: We retrospectively reviewed 30 patients with esophageal squamous cell carcinoma. All patients received definitive CRT. The relationship between the accumulation of 18F-FDG PET or 18F-FAMT PET in LNs prior to CRT and clinical outcomes was assessed. Results: A correlation was observed between LNs in which most of 18F-FAMT was accumulated and complete response (CR) rate, but was not for 18F-FDG. Additionally, for 18F-FAMT, the CR rate was significantly higher in the LN accumulated lesion ≤1 group than in the LN accumulated lesion >2 group. Discussion: To predict the outcome of definitive CRT in patients with esophageal cancer, it is important to evaluate the LN status.