TY - JOUR T1 - L-[3-<sup>18</sup>F]-α-Methyltyrosine Uptake by Lymph Node Metastasis Is a Predictor of Complete Response to CRT in Esophageal Cancer JF - Anticancer Research JO - Anticancer Res SP - 7473 LP - 7477 VL - 34 IS - 12 AU - MAKOTO SOHDA AU - TATSUYA MIYAZAKI AU - HIROAKI HONJYO AU - KEIGO HARA AU - DAIGO OZAWA AU - SHIGEMASA SUZUKI AU - NARITAKA TANAKA AU - AKIHIKO SANO AU - MAKOTO SAKAI AU - TAKEHIKO YOKOBORI AU - MASANOBU NAKAJIMA AU - MINORU FUKUCHI AU - HIROYUKI KATO AU - TETSUYA HIGUCHI AU - YOSHITO TSUSHIMA AU - HIROYUKI KUWANO Y1 - 2014/12/01 UR - http://ar.iiarjournals.org/content/34/12/7473.abstract N2 - Background/Aim: The amino acid positron emission tomography (PET) tracer [18F]-3-fluoro-alpha-methyltyrosine (18F-FAMT) is known to be highly specific for malignancies. We evaluated the accumulation of 18F-FDG or 18F-FAMT in lymph nodes (LN) prior to definitive chemoradiotherapy (CRT) for esophageal cancer. Patients and Methods: We retrospectively reviewed 30 patients with esophageal squamous cell carcinoma. All patients received definitive CRT. The relationship between the accumulation of 18F-FDG PET or 18F-FAMT PET in LNs prior to CRT and clinical outcomes was assessed. Results: A correlation was observed between LNs in which most of 18F-FAMT was accumulated and complete response (CR) rate, but was not for 18F-FDG. Additionally, for 18F-FAMT, the CR rate was significantly higher in the LN accumulated lesion ≤1 group than in the LN accumulated lesion &gt;2 group. Discussion: To predict the outcome of definitive CRT in patients with esophageal cancer, it is important to evaluate the LN status. ER -