PT  - JOURNAL ARTICLE
AU  - BACALBASA, NICOLAE
AU  - DIMA, SIMONA OLIMPIA
AU  - PURTAN-PURNICHESCU, RALUCA
AU  - HERLEA, VLAD
AU  - POPESCU, IRINEL
TI  - Role of Surgical Treatment in Breast Cancer Liver Metastases: A Single Center Experience
DP  - 2014 Oct 01
TA  - Anticancer Research
PG  - 5563--5568
VI  - 34
IP  - 10
4099  - http://ar.iiarjournals.org/content/34/10/5563.short
4100  - http://ar.iiarjournals.org/content/34/10/5563.full
SO  - Anticancer Res2014 Oct 01; 34
AB  - Background/Aim: The aim of the present study was to review a single hepatobiliary center experience, the benefit of hepatic metastasectomy in breast cancer liver metastases (BCLM) patients and to identify predictors of survival. Patients and Methods: Fifty-two female patients underwent surgery for BCLM between 2002 and 2013. Only patients with liver resections (n=43) were included in the analysis. Results: The median survival of the 43 patients with liver resection was 32.2 months. The factors significantly associated with overall post-hepatectomy survival were estrogen/progesteron receptor (ER/PR) status (p=0.002), node involvement of the primary tumor (p=0.049), size (p=0.005) and number (p=0.006) of the metastatic lesions. The 1-, 3- and 5-year survival rates after curative liver resection were 93.02%, 74.42%, 58.14%, respectively. Conclusion: BCLM resection is a safe procedure and offers survival benefit, especially in patients with reduced liver metastatic burden (solitary metastases, diameter of the metastases <5 cm) and positive ER/PR status.