<?xml version='1.0' encoding='UTF-8'?><xml><records><record><source-app name="HighWire" version="7.x">Drupal-HighWire</source-app><ref-type name="Journal Article">17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">IIDA, MASAKI</style></author><author><style face="normal" font="default" size="100%">TAKAYAMA, EIJI</style></author><author><style face="normal" font="default" size="100%">NAGANAWA, KOSUKE</style></author><author><style face="normal" font="default" size="100%">MITSUDO, KENJI</style></author><author><style face="normal" font="default" size="100%">ADACHI, MAKOTO</style></author><author><style face="normal" font="default" size="100%">BABA, JUN-ICHI</style></author><author><style face="normal" font="default" size="100%">FUJIMOTO-MUTO, MASAKO</style></author><author><style face="normal" font="default" size="100%">MOTOHASHI, MASAYUKI</style></author><author><style face="normal" font="default" size="100%">MIZUNO-KAMIYA, MASAKO</style></author><author><style face="normal" font="default" size="100%">KAWAKI, HARUMI</style></author><author><style face="normal" font="default" size="100%">KIOI, MITOMU</style></author><author><style face="normal" font="default" size="100%">ICHINOSE, MASAO</style></author><author><style face="normal" font="default" size="100%">SUMITOMO, SHIN-ICHIRO</style></author><author><style face="normal" font="default" size="100%">MURAMATSU, YASUNORI</style></author><author><style face="normal" font="default" size="100%">SHIKIMORI, MICHIO</style></author><author><style face="normal" font="default" size="100%">TOHNAI, IWAI</style></author><author><style face="normal" font="default" size="100%">KONDOH, NOBUO</style></author></authors><secondary-authors></secondary-authors></contributors><titles><title><style face="normal" font="default" size="100%">Increase of Peripheral Blood CD57&lt;sup&gt;+&lt;/sup&gt; T-Cells in Patients with Oral Squamous Cell Carcinoma</style></title><secondary-title><style face="normal" font="default" size="100%">Anticancer Research</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2014-10-01 00:00:00</style></date></pub-dates></dates><pages><style  face="normal" font="default" size="100%">5729-5734</style></pages><volume><style face="normal" font="default" size="100%">34</style></volume><issue><style face="normal" font="default" size="100%">10</style></issue><abstract><style  face="normal" font="default" size="100%">Background/Aim: The subset of T-cells positive for expression of cluster of differentiation (CD) 57 has been associated with various cancer phenotypes. However, the presence of CD57+ T-cells in patients with oral squamous cell carcinoma (OSCC) has yet to be confirmed. In the present study, we examined the diagnostic significance of the presence of CD57+ T-cells in peripheral blood (PB) from patients with OSCC. Materials and Methods: The subset of CD57+ T-cells in PB was analyzed in 43 patients with OSCC by fluorescence-activated cell sorting (FACS) analysis. Results: The proportion of CD57+ T-cells, including both CD8+ and CD4+ subsets, significantly increased with clinical stage, especially in parallel with tumor size. Conclusion: Our results suggest that an increase in the population of CD57+ T-cells is a potent prognostic marker and may also influence the systemic immunity of patients with OSCC.</style></abstract></record></records></xml>