TY - JOUR T1 - Predicting Overall Survival in Patients with Brain Metastases from Esophageal Cancer JF - Anticancer Research JO - Anticancer Res SP - 6763 LP - 6765 VL - 34 IS - 11 AU - DIRK RADES AU - LIESA DZIGGEL AU - TOBIAS BARTSCHT AU - JAN GLIEMROTH Y1 - 2014/11/01 UR - http://ar.iiarjournals.org/content/34/11/6763.abstract N2 - Aim: To identify survival predictors and develop a survival score for patients with brain metastases from esophageal cancer. Patients and Methods: In 16 patients, seven factors were analyzed including age, gender, Karnofsky performance score (KPS), time from diagnosis of esophageal cancer to irradiation, number of brain metastases, histology, and presence of extracerebral metastases. Results: Improved survival was significantly associated with KPS ≥80 (p<0.001), the presence of one brain metastasis (p=0.007), and no extra-cerebral metastases (p=0.002). These factors were included in the final score. Factor scores were calculated by dividing 6-month survival rates by 10. Total survival scores represented the sums of factor scores and were 2, 7, 10, 19 or 24 points. Six-month survival rates by score were 0%, 0%, 0%, 67% and 100%, respectively. Two groups were formed, those of patients with 2-10 points and those with 19-24 points; 6-month survival was 0% and 88%, respectively (p<0.001). Conclusion: This new score facilitates the selection of individual therapies for patients with brain metastases from esophageal cancer. ER -