RT Journal Article
SR Electronic
T1 Vincristine-induced Blindness: A Case Report and Review of Literature
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 6731
OP 6733
VO 34
IS 11
A1 ADHIKARI, SUBODH
A1 DONGOL, RAJ MAN
A1 HEWETT, YVONNE
A1 SHAH, BINAY KUMAR
YR 2014
UL http://ar.iiarjournals.org/content/34/11/6731.abstract
AB Background: Neurotoxicity is a dose-limiting side-effect of vincristine therapy. Blindness is a rare central neurotoxicity of vincristine with few case reports. Case report: In the present article, we report a rare case of vincristine-induced blindness in a patient with diffuse large B cell lymphoma. Literature search identified eleven published cases of vincristine-induced blindness. We reviewed patient characteristics, chemotherapy used and type of blindness. Conclusion: Vincristine-induced blindness is rare and unpredictable. Prompt recognition and discontinuation of vincristine may lead to recovery of vision.