TY - JOUR T1 - Vincristine-induced Blindness: A Case Report and Review of Literature JF - Anticancer Research JO - Anticancer Res SP - 6731 LP - 6733 VL - 34 IS - 11 AU - SUBODH ADHIKARI AU - RAJ MAN DONGOL AU - YVONNE HEWETT AU - BINAY KUMAR SHAH Y1 - 2014/11/01 UR - http://ar.iiarjournals.org/content/34/11/6731.abstract N2 - Background: Neurotoxicity is a dose-limiting side-effect of vincristine therapy. Blindness is a rare central neurotoxicity of vincristine with few case reports. Case report: In the present article, we report a rare case of vincristine-induced blindness in a patient with diffuse large B cell lymphoma. Literature search identified eleven published cases of vincristine-induced blindness. We reviewed patient characteristics, chemotherapy used and type of blindness. Conclusion: Vincristine-induced blindness is rare and unpredictable. Prompt recognition and discontinuation of vincristine may lead to recovery of vision. ER -