PT  - JOURNAL ARTICLE
AU  - ADHIKARI, SUBODH
AU  - DONGOL, RAJ MAN
AU  - HEWETT, YVONNE
AU  - SHAH, BINAY KUMAR
TI  - Vincristine-induced Blindness: A Case Report and Review of Literature
DP  - 2014 Nov 01
TA  - Anticancer Research
PG  - 6731--6733
VI  - 34
IP  - 11
4099  - http://ar.iiarjournals.org/content/34/11/6731.short
4100  - http://ar.iiarjournals.org/content/34/11/6731.full
SO  - Anticancer Res2014 Nov 01; 34
AB  - Background: Neurotoxicity is a dose-limiting side-effect of vincristine therapy. Blindness is a rare central neurotoxicity of vincristine with few case reports. Case report: In the present article, we report a rare case of vincristine-induced blindness in a patient with diffuse large B cell lymphoma. Literature search identified eleven published cases of vincristine-induced blindness. We reviewed patient characteristics, chemotherapy used and type of blindness. Conclusion: Vincristine-induced blindness is rare and unpredictable. Prompt recognition and discontinuation of vincristine may lead to recovery of vision.