RT Journal Article
SR Electronic
T1 The Intercellular Cell Adhesion Molecule-1 (ICAM-1) in Lung Cancer: Implications for Disease Progression and Prognosis
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 4665
OP 4672
VO 34
IS 9
A1 KOTTEAS, ELIAS A.
A1 BOULAS, PANAGIOTIS
A1 GKIOZOS, IOANNIS
A1 TSAGKOULI, SOFIA
A1 TSOUKALAS, GEORGE
A1 SYRIGOS, KONSTANTINOS N.
YR 2014
UL http://ar.iiarjournals.org/content/34/9/4665.abstract
AB The intercellular cell-adhesion molecule-1 (ICAM-1) is a transmembrane molecule and a distinguished member of the Immunoglobulin superfamily of proteins that participates in many important processes, including leukocyte endothelial transmigration, cell signaling, cell-cell interaction, cell polarity and tissue stability. ICAM-1and its soluble part are highly expressed in inflammatory conditions, chronic diseases and a number of malignancies. In the present article we present the implications of ICAM-1 in the progression and prognosis of one of the major global killers of our era: lung cancer.