PT  - JOURNAL ARTICLE
AU  - ELIAS A. KOTTEAS
AU  - PANAGIOTIS BOULAS
AU  - IOANNIS GKIOZOS
AU  - SOFIA TSAGKOULI
AU  - GEORGE TSOUKALAS
AU  - KONSTANTINOS N. SYRIGOS
TI  - The Intercellular Cell Adhesion Molecule-1 (ICAM-1) in Lung Cancer: Implications for Disease Progression and Prognosis
DP  - 2014 Sep 01
TA  - Anticancer Research
PG  - 4665--4672
VI  - 34
IP  - 9
4099  - http://ar.iiarjournals.org/content/34/9/4665.short
4100  - http://ar.iiarjournals.org/content/34/9/4665.full
SO  - Anticancer Res2014 Sep 01; 34
AB  - The intercellular cell-adhesion molecule-1 (ICAM-1) is a transmembrane molecule and a distinguished member of the Immunoglobulin superfamily of proteins that participates in many important processes, including leukocyte endothelial transmigration, cell signaling, cell-cell interaction, cell polarity and tissue stability. ICAM-1and its soluble part are highly expressed in inflammatory conditions, chronic diseases and a number of malignancies. In the present article we present the implications of ICAM-1 in the progression and prognosis of one of the major global killers of our era: lung cancer.