RT Journal Article
SR Electronic
T1 Prevalence of Perfusion Defects Detected by Stress <sup>99m</sup>Technetium Sestamibi Myocardial Perfusion Single-photon Emission Computed Tomography in Asymptomatic Patients with Breast Cancer
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 3689
OP 3694
VO 34
IS 7
A1 BOHUSLAV MELICHAR
A1 JIŘÍ DOLEŽAL
A1 VLASTISLAV ŠRÁMEK
A1 HANA KALÁBOVÁ
A1 LENKA KUJOVSKÁ KRČMOVÁ
A1 RADOMÍR HYŠPLER
A1 HANA ŠTUDENTOVÁ
A1 MILAN VOŠMIK
A1 MIROSLAV PECKA
A1 ADAM SVOBODNÍK
A1 LADISLAV PECEN
A1 MARTIN DOLEŽEL
A1 DAGMAR SOLICHOVÁ
YR 2014
UL http://ar.iiarjournals.org/content/34/7/3689.abstract
AB Aim: The aim of the present study was to investigate myocardial perfusion in relation to disease history and laboratory parameters of atherosclerosis risk in asymptomatic patients with breast carcinoma. Patients and Methods: One-hundred and eighty-one patients with breast carcinoma were studied. Myocardial perfusion was assessed using single-photon emission computed tomography (SPECT) with 99mtechnetium sestamibi. Results: Perfusion defects were detected in 12 patients (7%). Higher body-mass index, increased concentrations of D-dimers, C-reactive protein, fibrinogen, glucose, triglycerides, and urinary albumin, a history of hypertension and of radiotherapy to the left chest wall were all associated with increased risk of perfusion defects. In a multivariate stepwise selection logistic regression model, body mass index, albuminuria and radiotherapy to the left hemithorax were significantly associated with the presence of perfusion defects. Conclusion: In addition to other factors, treatment history may be associated with the presence of perfusion defects in patients with breast cancer.