TY - JOUR T1 - Prevalence of Perfusion Defects Detected by Stress <sup>99m</sup>Technetium Sestamibi Myocardial Perfusion Single-photon Emission Computed Tomography in Asymptomatic Patients with Breast Cancer JF - Anticancer Research JO - Anticancer Res SP - 3689 LP - 3694 VL - 34 IS - 7 AU - BOHUSLAV MELICHAR AU - JIŘÍ DOLEŽAL AU - VLASTISLAV ŠRÁMEK AU - HANA KALÁBOVÁ AU - LENKA KUJOVSKÁ KRČMOVÁ AU - RADOMÍR HYŠPLER AU - HANA ŠTUDENTOVÁ AU - MILAN VOŠMIK AU - MIROSLAV PECKA AU - ADAM SVOBODNÍK AU - LADISLAV PECEN AU - MARTIN DOLEŽEL AU - DAGMAR SOLICHOVÁ Y1 - 2014/07/01 UR - http://ar.iiarjournals.org/content/34/7/3689.abstract N2 - Aim: The aim of the present study was to investigate myocardial perfusion in relation to disease history and laboratory parameters of atherosclerosis risk in asymptomatic patients with breast carcinoma. Patients and Methods: One-hundred and eighty-one patients with breast carcinoma were studied. Myocardial perfusion was assessed using single-photon emission computed tomography (SPECT) with 99mtechnetium sestamibi. Results: Perfusion defects were detected in 12 patients (7%). Higher body-mass index, increased concentrations of D-dimers, C-reactive protein, fibrinogen, glucose, triglycerides, and urinary albumin, a history of hypertension and of radiotherapy to the left chest wall were all associated with increased risk of perfusion defects. In a multivariate stepwise selection logistic regression model, body mass index, albuminuria and radiotherapy to the left hemithorax were significantly associated with the presence of perfusion defects. Conclusion: In addition to other factors, treatment history may be associated with the presence of perfusion defects in patients with breast cancer. ER -