PT  - JOURNAL ARTICLE
AU  - BOHUSLAV MELICHAR
AU  - JIŘÍ DOLEŽAL
AU  - VLASTISLAV ŠRÁMEK
AU  - HANA KALÁBOVÁ
AU  - LENKA KUJOVSKÁ KRČMOVÁ
AU  - RADOMÍR HYŠPLER
AU  - HANA ŠTUDENTOVÁ
AU  - MILAN VOŠMIK
AU  - MIROSLAV PECKA
AU  - ADAM SVOBODNÍK
AU  - LADISLAV PECEN
AU  - MARTIN DOLEŽEL
AU  - DAGMAR SOLICHOVÁ
TI  - Prevalence of Perfusion Defects Detected by Stress <sup>99m</sup>Technetium Sestamibi Myocardial Perfusion Single-photon Emission Computed Tomography in Asymptomatic Patients with Breast Cancer
DP  - 2014 Jul 01
TA  - Anticancer Research
PG  - 3689--3694
VI  - 34
IP  - 7
4099  - http://ar.iiarjournals.org/content/34/7/3689.short
4100  - http://ar.iiarjournals.org/content/34/7/3689.full
SO  - Anticancer Res2014 Jul 01; 34
AB  - Aim: The aim of the present study was to investigate myocardial perfusion in relation to disease history and laboratory parameters of atherosclerosis risk in asymptomatic patients with breast carcinoma. Patients and Methods: One-hundred and eighty-one patients with breast carcinoma were studied. Myocardial perfusion was assessed using single-photon emission computed tomography (SPECT) with 99mtechnetium sestamibi. Results: Perfusion defects were detected in 12 patients (7%). Higher body-mass index, increased concentrations of D-dimers, C-reactive protein, fibrinogen, glucose, triglycerides, and urinary albumin, a history of hypertension and of radiotherapy to the left chest wall were all associated with increased risk of perfusion defects. In a multivariate stepwise selection logistic regression model, body mass index, albuminuria and radiotherapy to the left hemithorax were significantly associated with the presence of perfusion defects. Conclusion: In addition to other factors, treatment history may be associated with the presence of perfusion defects in patients with breast cancer.