TY - JOUR T1 - Prognostic Significance of Pre- and Postoperative Glasgow Prognostic Score for Patients with Non-small Cell Lung Cancer JF - Anticancer Research JO - Anticancer Res SP - 3137 LP - 3140 VL - 34 IS - 6 AU - MASAKI TOMITA AU - TAKANORI AYABE AU - EIICHI CHOSA AU - KUNIHIDE NAKAMURA Y1 - 2014/06/01 UR - http://ar.iiarjournals.org/content/34/6/3137.abstract N2 - Background: Our previous study showed the prognostic impact of preoperative Glasgow prognostic score (GPS) in patients who underwent resection for non-small cell lung cancer (NSCLC). In the present study, the relationship between postoperative GPS and prognosis was also examined in patients with NSCLC with preoperative GPS 1 or 2. Patients and Methods: Three hundred and twelve consecutive patients resected for NSCLC with a follow-up period of more than five years were enrolled. The GPS was calculated as follows: patients with elevated C-reactive protein level (>1.0 mg/dl) and hypoalbuminemia (<3.5 g/dl) were assigned to GPS 2. Patients with one or no abnormal value were assigned to GPS 1 or GPS 0. Results: Study patients were allocated as follows: 264 (84.62%) to GPS 0; 31 (9.94%) to GPS 1; and 17 (5.45%) to GPS 2. The prognosis of the patients with preoperative GPS 2 was significantly poorer. Postoperative GPS was also examined for 48 patients with preoperative GPS 1 or 2. In 30/48 patients, postoperative GPS was improved to GPS 0, however, the postoperative GPS of the remaining 18 patients did not change to GPS 0. The 5-year survival of patients with postoperative GPS 0 and 1-2 were 73.02% and 11.11%, respectively. Conclusion: Preoperative GPS may be useful for postoperative prognosis of patients with NSCLC. Furthermore, persistently high GPS after surgery indicates poor prognosis in patients with NSCLC. ER -