@article {TOMITA3137, author = {MASAKI TOMITA and TAKANORI AYABE and EIICHI CHOSA and KUNIHIDE NAKAMURA}, title = {Prognostic Significance of Pre- and Postoperative Glasgow Prognostic Score for Patients with Non-small Cell Lung Cancer}, volume = {34}, number = {6}, pages = {3137--3140}, year = {2014}, publisher = {International Institute of Anticancer Research}, abstract = {Background: Our previous study showed the prognostic impact of preoperative Glasgow prognostic score (GPS) in patients who underwent resection for non-small cell lung cancer (NSCLC). In the present study, the relationship between postoperative GPS and prognosis was also examined in patients with NSCLC with preoperative GPS 1 or 2. Patients and Methods: Three hundred and twelve consecutive patients resected for NSCLC with a follow-up period of more than five years were enrolled. The GPS was calculated as follows: patients with elevated C-reactive protein level (\>1.0 mg/dl) and hypoalbuminemia (\<3.5 g/dl) were assigned to GPS 2. Patients with one or no abnormal value were assigned to GPS 1 or GPS 0. Results: Study patients were allocated as follows: 264 (84.62\%) to GPS 0; 31 (9.94\%) to GPS 1; and 17 (5.45\%) to GPS 2. The prognosis of the patients with preoperative GPS 2 was significantly poorer. Postoperative GPS was also examined for 48 patients with preoperative GPS 1 or 2. In 30/48 patients, postoperative GPS was improved to GPS 0, however, the postoperative GPS of the remaining 18 patients did not change to GPS 0. The 5-year survival of patients with postoperative GPS 0 and 1-2 were 73.02\% and 11.11\%, respectively. Conclusion: Preoperative GPS may be useful for postoperative prognosis of patients with NSCLC. Furthermore, persistently high GPS after surgery indicates poor prognosis in patients with NSCLC.}, issn = {0250-7005}, URL = {https://ar.iiarjournals.org/content/34/6/3137}, eprint = {https://ar.iiarjournals.org/content/34/6/3137.full.pdf}, journal = {Anticancer Research} }