PT  - JOURNAL ARTICLE
AU  - DI FRANCO, ROSSELLA
AU  - FALIVENE, SARA
AU  - RAVO, VINCENZO
AU  - MAMMUCARI, MASSIMO
AU  - SARLI, ENNIO
AU  - BAFFINI, STELLA
AU  - DE PALMA, GIAMPAOLO
AU  - PEPE, ALFONSINA
AU  - TRAETTINO, MARIANNA
AU  - MUTO, MATTEO
AU  - CAPPABIANCA, SALVATORE
AU  - MUTO, PAOLO
TI  - Management of Painful Bone Metastases: Our Experience According to Scientific Evidence on Palliative Radiotherapy
DP  - 2014 Feb 01
TA  - Anticancer Research
PG  - 1011--1014
VI  - 34
IP  - 2
4099  - http://ar.iiarjournals.org/content/34/2/1011.short
4100  - http://ar.iiarjournals.org/content/34/2/1011.full
SO  - Anticancer Res2014 Feb 01; 34
AB  - Aim: Our aim was to evaluate retrospectively the role of the radiotherapy in the multi-disciplinary management of pain due to bone metastases. Patients and Methods: A total of 305 patients received radiotherapy with or without bisphosphonate and antalgic drugs. Tolerability and efficacy were evaluated using a Numerical Rating Scale, Pain Intensity Difference evaluation scale related to administration of the drug, a 5-point verbal scale of the patients' general impression. Results: We found differences in some patient subgroups: pain reduction was significantly more evident in patients treated with a single-fraction radiotherapy scheme. Overall, 68% of patients experienced an improvement in pain control using concomitant drugs during radiotherapy. Conclusion: Our study underlines the role of radiotherapy in the management of metastatic bone pain. The use of rapid-onset opioids to prevent predictable pain is a crucial step in managing radiotherapy. An interdisciplinary approach is recommended.