PT  - JOURNAL ARTICLE
AU  - SEUNG-HYUK SHIM
AU  - SUN JOO LEE
AU  - DAE-YEON KIM
AU  - JIN KIM
AU  - SOO-NYUNG KIM
AU  - SOON-BEOM KANG
AU  - JONG-HYEOK KIM
AU  - YONG-MAN KIM
AU  - YOUNG-TAK KIM
AU  - JOO-HYUN NAM
TI  - A Long-term Follow-up Study of 91 Cases with Ovarian Granulosa Cell Tumors
DP  - 2014 Feb 01
TA  - Anticancer Research
PG  - 1001--1010
VI  - 34
IP  - 2
4099  - http://ar.iiarjournals.org/content/34/2/1001.short
4100  - http://ar.iiarjournals.org/content/34/2/1001.full
SO  - Anticancer Res2014 Feb 01; 34
AB  - Aim: To evaluate the prognostic factors of ovarian granulosa cell tumors (GCTs) and treatment outcomes in recurrent GCT cases. Patients and Methods: We retrospectively reviewed 91 patients with GCT who were treated in two tertiary Centers between 1989 and 2011. Results: Eighty patients had stage I tumors, five had stage II, and six had stage III. There were 15 cases of recurrence with a median follow-up time of 58 (3-254) months. Multivariate analysis identified greater tumor size and postoperative residual tumor as independent risk factors for recurrence. Twelve patients underwent secondary surgery at first recurrence. At a median follow-up of 50 (4-185) months from first recurrence, the 5-year survival was 60% for patients with and 100% for those without residual tumor after secondary surgery, respectively (p=0.018, log-rank test). Conclusion: Complete cytoreduction is an important prognostic factor for recurrent cases as well as initial treatment of GCT.