TY - JOUR T1 - Esophageal Stenosis: A Differential Diagnosis Between Esophageal Cancer and Metastasis from Other Neoplasia JF - Anticancer Research JO - Anticancer Res SP - 363 LP - 366 VL - 34 IS - 1 AU - IDA PARIS AU - ARSELA PRELAJ AU - CONCETTA ELISA ONESTI AU - ALESSANDRA BALDONI AU - MARIA ROSARIA GIOVAGNOLI AU - MARIA BASSANELLI AU - SALVATORE LAURO AU - PAOLO MARCHETTI Y1 - 2014/01/01 UR - http://ar.iiarjournals.org/content/34/1/363.abstract N2 - Background: The occurrence of radiological mediastinal lymphadenopathy as the only evidence of tumor recurrence of cervical carcinoma is very rare. We report on such a case with stenosis of the esophagus. Case Report: A 36-year-old Caucasian woman, without any relevant history of gynecological cancer, underwent a trans-vaginal ultrasound with evidence of any cervical lesion locally extended. After histologically-proven diagnosis of squamous cell carcinoma of the cervix uterine, the patient was treated by neoadjuvant chemoradiation, followed by total abdominal hysterectomy with bilateral salpingoophorectomy. A subsequent close follow-up was negative for recurrence of disease until December 2008, two years after diagnosis. At that period, the patient experienced cough and severe dysphagia and for this reason she underwent several examinations including esophagogastroduodenoscopy, whole-body computed tomographic scan and bronchoscopy with transbronchial needle aspiration. Histology led to diagnosis of recurrence of cervical cancer, HPV31-positive, in multiple mediastinal lymphnodes, with infiltration of the esophageal mucosa. Conclusion: Mediastinal lymphade-nopathy in patients with a history of cervical carcinoma should be suspicious of metastatic disease, even if there is no radiological evidence of distant metastases. ER -