RT Journal Article SR Electronic T1 Detection of Lung Cancer by FDG-PET Cancer Screening Program: A Nationwide Japanese Survey JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 183 OP 189 VO 34 IS 1 A1 RYOGO MINAMIMOTO A1 MICHIO SENDA A1 SEISHI JINNOUCHI A1 TAKASHI TERAUCHI A1 TSUYOSHI YOSHIDA A1 KIMIICHI UNO A1 TAKESHI IINUMA A1 TAKESHI MURANO A1 RUMI NAKASHIMA A1 TOMIO INOUE YR 2014 UL http://ar.iiarjournals.org/content/34/1/183.abstract AB Aim: The aim of this study was to analyze the lung cancer detection rate in asymptomatic individuals by the Fluorine-18 fluorodeoxyglucose-positron emission tomography FDG-PET cancer screening program in Japan. Materials and Methods: A total of 153,775 asymptomatic individuals underwent the FDG-PET cancer screening program; the 854 cases with findings that indicated suspected lung cancer by any detection method were analyzed. Results: Among the 854 cases, 319 were verified as lung cancer. The relative sensitivity and positive predictive value (PPV) of FDG-PET were 86.5% and 38.9% for lung cancer, respectively. The sensitivity of PET/computed tomography (CT) scanner was higher than that of dedicated PET (100.0% vs. 63.2%), indicating that CT imaging was effective for lung cancer screening. The majority of lung carcinomas detected by FDG-PET screening were UICC stage IA or IB, but detection of smaller or less invasive carcinomas was limited. Conclusion: The FDG-PET screening program in Japan detected lung cancer at an early stage.