RT Journal Article
SR Electronic
T1 Factors Predictive of Oncological Outcome After Nephroureterectomy: Comparison Between Laparoscopic and Open Procedures
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 5501
OP 5506
VO 33
IS 12
A1 KOUJI IZUMI
A1 SHINGO ITAI
A1 YOSHIKO TAKAHASHI
A1 RIE TAKAHASHI
A1 AERKEN MAOLAKE
A1 MITSUO OFUDE
A1 SATORU UENO
A1 YOSHIFUMI KADONO
A1 YASUHIDE KITAGAWA
A1 HIROYUKI KONAKA
A1 ATSUSHI MIZOKAMI
A1 MIKIO NAMIKI
YR 2013
UL http://ar.iiarjournals.org/content/33/12/5501.abstract
AB Background: Although laparoscopic radical nephroureterectomy is the standard treatment for localized upper urinary tract urothelial carcinoma, open radical nephroureterectomy has been reported to have a different rate of intravesical recurrence. Patients and Methods: Intravesical recurrence-free, progression-free, and overall survival rates among patients undergoing open and laparoscopic radical nephroureterectomy from 2002 to 2013 were analyzed. Results: Although no single factor predicted intravesical recurrence-free survival, a past history of bladder cancer or grade 3 was related to poorer intravesical recurrence-free survival rate in patients treated with laparoscopic radical nephroureterectomy. Moreover, the novel proposed risk classification based on our data clearly showed better progression-free survival and overall survival, as well as intravesical recurrence-free survival, in patients treated with laparoscopic radical nephroureterectomy. Conclusion: The findings reported here may help urologists predict oncological outcomes and to plan follow-up schedules after laparoscopic radical nephroureterectomy.