RT Journal Article SR Electronic T1 Chemoprevention of Prostate Cancer by Major Dietary Phytochemicals JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 4163 OP 4174 VO 33 IS 10 A1 AJAY BOMMAREDDY A1 WILLIAM EGGLESTON A1 STACY PRELEWICZ A1 ANDREA ANTAL A1 ZBIGNIEW WITCZAK A1 DAN F. MCCUNE A1 ADAM L. VANWERT YR 2013 UL http://ar.iiarjournals.org/content/33/10/4163.abstract AB Prostate cancer continues to be one of the most commonly diagnosed diseases and the second leading cause of cancer-related deaths among men in the United States. Options exist to treat localized disease, including surgery, radiation therapy, and hormonal therapy, but clinical management of advanced prostate cancer is challenging. In the past few decades, chemoprevention involving naturally-occurring compounds has emerged as a promising and cost-effective approach to reduce incidence and morbidity of prostate cancer by inhibiting the precancerous events before the occurrence of clinical disease. The present review focuses on summarizing the recent advances in studies of major dietary phytochemicals and their role in prostate cancer development.