TY - JOUR T1 - Fatal Herpes Encephalitis in a Patient with Small Cell Lung Cancer Following Prophylactic Cranial Radiation - A Case Report with Review of Literature JF - Anticancer Research JO - Anticancer Res SP - 3263 LP - 3268 VL - 33 IS - 8 AU - SUBHANKAR CHAKRABORTY AU - MICHAEL DONNER AU - DAVID COLAN Y1 - 2013/08/01 UR - http://ar.iiarjournals.org/content/33/8/3263.abstract N2 - Herpes simplex virus 1 (HSV-1) is the principal cause of viral necrotizing encephalitis in developed countries. Small cell carcinoma of the lung accounts for about 15% of all lung cancer. HSV induced encephalitis (HSE) following prophylactic cranial irradiation (PCI) in SCLC is rare. Here, we describe the case of a 58-year-old woman with limited stage SCLC, multiple sclerosis (MS) and cutaneous lupus who developed fatal HSE following PCI. We review the literature to investigate the inter-relationships between these diseases and management of HSE. ER -