TY - JOUR T1 - Prostate Cancer Detection at Repeat Biopsy: Can Pelvic Phased-array Multiparametric MRI Replace Saturation Biopsy? JF - Anticancer Research JO - Anticancer Res SP - 1195 LP - 1199 VL - 33 IS - 3 AU - PIETRO PEPE AU - ANTONIO GARUFI AU - GIANDOMENICO PRIOLO AU - GIUSEPPE CANDIANO AU - FRANCESCO PIETROPAOLO AU - MICHELE PENNISI AU - FILIPPO FRAGGETTA AU - FRANCESCO ARAGONA Y1 - 2013/03/01 UR - http://ar.iiarjournals.org/content/33/3/1195.abstract N2 - Aim: Magnetic resonance imaging (MRI) accuracy in prostate cancer (PCa) diagnosis in men submitted to saturation prostate biopsy (SPBx) was evaluated. Materials and Methods: From June 2011 to December 2012, 78 patients (median 63 years) underwent repeat SPBx (median 28 cores). Multiparametric MRI using a 3 Tesla pelvic phased-array coil was performed before SPBx and lesions suspicious for PCa were submitted to additional targeted biopsies. Results: A T1c PCa was found in 32 (41%) cases. SPBx vs. MRI-suspicious targeted biopsy diagnosed 28 (87.5%) vs. 26 (81.2%) PCa missing four (12.5%) and six (18.8%) cancers localized in the anterior zone and in the lateral margin of the prostate, respectively; moreover, MRI diameter lesions correlated with PCa diagnosis and Gleason score (p<0.05). Conclusion: Multiparametric MRI improved SPBx accuracy in diagnosing PCa of the anterior zone; moreover, suspicious areas >10 mm resulted as highly predictive of cancer (about 70% of the cases). ER -