@article {PEPE1195, author = {PIETRO PEPE and ANTONIO GARUFI and GIANDOMENICO PRIOLO and GIUSEPPE CANDIANO and FRANCESCO PIETROPAOLO and MICHELE PENNISI and FILIPPO FRAGGETTA and FRANCESCO ARAGONA}, title = {Prostate Cancer Detection at Repeat Biopsy: Can Pelvic Phased-array Multiparametric MRI Replace Saturation Biopsy?}, volume = {33}, number = {3}, pages = {1195--1199}, year = {2013}, publisher = {International Institute of Anticancer Research}, abstract = {Aim: Magnetic resonance imaging (MRI) accuracy in prostate cancer (PCa) diagnosis in men submitted to saturation prostate biopsy (SPBx) was evaluated. Materials and Methods: From June 2011 to December 2012, 78 patients (median 63 years) underwent repeat SPBx (median 28 cores). Multiparametric MRI using a 3 Tesla pelvic phased-array coil was performed before SPBx and lesions suspicious for PCa were submitted to additional targeted biopsies. Results: A T1c PCa was found in 32 (41\%) cases. SPBx vs. MRI-suspicious targeted biopsy diagnosed 28 (87.5\%) vs. 26 (81.2\%) PCa missing four (12.5\%) and six (18.8\%) cancers localized in the anterior zone and in the lateral margin of the prostate, respectively; moreover, MRI diameter lesions correlated with PCa diagnosis and Gleason score (p\<0.05). Conclusion: Multiparametric MRI improved SPBx accuracy in diagnosing PCa of the anterior zone; moreover, suspicious areas \>10 mm resulted as highly predictive of cancer (about 70\% of the cases).}, issn = {0250-7005}, URL = {https://ar.iiarjournals.org/content/33/3/1195}, eprint = {https://ar.iiarjournals.org/content/33/3/1195.full.pdf}, journal = {Anticancer Research} }