RT Journal Article SR Electronic T1 Computer-assisted Diagnosis (CAD) in Colposcopy: Evaluation of a Pilot Study JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 5221 OP 5226 VO 32 IS 12 A1 GRIT MEHLHORN A1 ANDREAS KAGE A1 CHRISTIAN MÜNZENMAYER A1 MICHAELA BENZ A1 MARTIN C. KOCH A1 MATTHIAS W. BECKMANN A1 THOMAS WITTENBERG YR 2012 UL http://ar.iiarjournals.org/content/32/12/5221.abstract AB Background: A prototype system for computer-assisted colposcopic diagnosis (CAD) currently achieves a high level of accuracy of 80% (sensitivity 85%, specificity 75%) for the automatic assessment of colposcopic images. This pilot study investigated whether this type of CAD system is, in principle, capable of influencing the quality of the examiner's assessment. Materials and Methods: In this observer study, 24 digitized colposcopic images from patients attending a dysplasia clinic were assessed by 90 participants. All participants had attended a colposcopy training workshop so that they acquired the same basic information and skills. Results: Wide variation was seen among the non-experts, in contrast to the experts. An overall improvement in diagnostic accuracy was noted when the CAD system was used (non-experts: sensitivity 78%, specificity 70%; experts: sensitivity 74%, specificity 70%). Conclusion: The CAD system may serve as an aid in the further diagnosis of cervical intraepithelial neoplasia, and has the potential to improve the diagnostic process.