@article {SAARTO3875, author = {TIINA SAARTO and HEIDI MARIKA PENTTINEN and HARRI SIEV{\"A}NEN and PIRKKO-LIISA KELLOKUMPU-LEHTINEN and LIISA HAKAMIES-BLOMQVIST and RIKU NIKANDER and RIIKKA HUOVINEN and RIITTA LUOTO and HANNU KAUTIAINEN and SALME J{\"A}RVENP{\"A}{\"A} and IRJA IDMAN and MERI UTRIAINEN and LEENA VEHMANEN and ANNA-STINA J{\"A}{\"A}SKEL{\"A}INEN and ANNELI ELME and JOHANNA RUOHOLA and TIINA PALVA and HARRI VERTIO and MATTI RAUTALAHTI and MIKAEL FOGELHOLM and CARL BLOMQVIST and MINNA-LIISA LUOMA}, title = {Effectiveness of a 12-month Exercise Program on Physical Performance and Quality of Life of Breast Cancer Survivors}, volume = {32}, number = {9}, pages = {3875--3884}, year = {2012}, publisher = {International Institute of Anticancer Research}, abstract = {Aim: The study aimed at determining whether physical exercise training improves the quality of life (QoL) and physical fitness of breast cancer survivors. Patients and Methods: A total of 573 breast cancer survivors were randomized into an exercise or a control group, 12-months after adjuvant treatments. EORTC QLQ-C30 and BR-23 questionnaires were used for evaluation of QoL, FACIT-F for fatigue and the Finnish modified version of Beck{\textquoteright}s 13-item depression scale (RBDI) for depression. Physical fitness was assessed by a 2-km walking test, and a figure-8 running test and physical activity (PA) by metabolic equivalent (MET) hours per week (MET-h/wk). Results: Figure-8 running time improved significantly among the patients of the intervention group compared with the controls (p\<0.001). No significant between-group differences were observed in 2-km walking time, in PA, EORTC-QLQ-C30, BR-23, FACIT-F or BDI. However, there was a linear relationship between increased PA and improved QoL (p=0.006), irrespective of the intervention. Conclusion: Increase in physical activity was associated with improved QoL, but no effect of the exercise intervention was observed.}, issn = {0250-7005}, URL = {https://ar.iiarjournals.org/content/32/9/3875}, eprint = {https://ar.iiarjournals.org/content/32/9/3875.full.pdf}, journal = {Anticancer Research} }