TY - JOUR T1 - Lymph Node Assessment with <sup>18</sup>F-FDG-PET and MRI in Uterine Cervical Cancer JF - Anticancer Research JO - Anticancer Res SP - 3865 LP - 3871 VL - 31 IS - 11 AU - JACQUES MONTEIL AU - ANTOINE MAUBON AU - SOPHIE LEOBON AU - SONIA ROUX AU - BENOIT MARIN AU - JOEL RENAUDIE AU - DOMINIQUE GENET AU - VÉRONIQUE FERMEAUX AU - YVES AUBARD AU - NICOLE TUBIANA-MATHIEU Y1 - 2011/11/01 UR - http://ar.iiarjournals.org/content/31/11/3865.abstract N2 - Background: To assess pelvic (P) and/or paraaortic (PA) lymph node (LN) involvement in patients with primary stage IA–IVA cervical cancer, 18F-fluorodeoxyglucose (FDG)-PET, and MRI were compared with histological results. Materials and Methods: Forty patients were prospectively evaluated. Twenty-eight patients underwent radio-chemotherapy (RT-CT) after initial staging and lymph node dissection (LND). Results: PLN metastases were present in 6/31 patients. Sensitivity, specificity, positive and negative predictive values (PPV, NPV) and accuracy in detecting PLN metastases were 67%, 84%, 50%, 91% and 81%, with MRI, and 33%, 92%, 50%, 85% and 81%, with FDG-PET. PALN metastases were present in 5/27 patients. Sensitivity, specificity, PPV, NPV and accuracy were 60%, 73%, 33%, 89% and 70% with MRI and 100%, 77%, 50%, 100% and 81% with FDG-PET in detecting PALN metastasis. Conclusion: FDG-PET is less accurate than MRI for PLN, but more accurate for PALN; FDG-PET cannot replace PA surgical procedures, but could guide them. ER -