RT Journal Article
SR Electronic
T1 Intraoperative Ultrasound: Improved Resection Rates in Breast-conserving Surgery
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 1051
OP 1056
VO 32
IS 3
A1 EICHLER, CHRISTIAN
A1 HÜBBEL, ANNETTE
A1 ZARGHOONI, VERENA
A1 THOMAS, ANKE
A1 GLUZ, OLEG
A1 STOFF-KHALILI, MARIAM
A1 WARM, MATHIAS
YR 2012
UL http://ar.iiarjournals.org/content/32/3/1051.abstract
AB Aim: The objective of this study was the investigation of a possible improvement of tumor resection rate, i.e. R0 vs. R1 resection when intraoperative ultrasound evaluation of tissue margins is used during breast-conserving surgery (BCS). Patients and Methods: A total of 250 cases were evaluated retrospectively. The impact of ultrasound analysis onto clean margin rates was evaluated. A subgroup analysis assessed histology, stage, and neoadjuvant therapy with respect to R0 resection rate and ultrasound evaluation. Results: Of 250 BCS cases 84, (33.6%) underwent intraoperative ultrasound and 166 (66.4%) did not. Clean primary surgical margins (R0) were demonstrated for 218 (87.2%) patients after histological analysis. R0 resection was achieved in 81 (96.4%) patients in the ultrasound group compared to 137 (82.5%) in the control group. The difference between the two groups is significant. Conclusion: This study revealed a significant increase in R0 resection rates when intraoperative ultrasound was used to evaluate surgical margins.