PT  - JOURNAL ARTICLE
AU  - EICHLER, CHRISTIAN
AU  - HÜBBEL, ANNETTE
AU  - ZARGHOONI, VERENA
AU  - THOMAS, ANKE
AU  - GLUZ, OLEG
AU  - STOFF-KHALILI, MARIAM
AU  - WARM, MATHIAS
TI  - Intraoperative Ultrasound: Improved Resection Rates in Breast-conserving Surgery
DP  - 2012 Mar 01
TA  - Anticancer Research
PG  - 1051--1056
VI  - 32
IP  - 3
4099  - http://ar.iiarjournals.org/content/32/3/1051.short
4100  - http://ar.iiarjournals.org/content/32/3/1051.full
SO  - Anticancer Res2012 Mar 01; 32
AB  - Aim: The objective of this study was the investigation of a possible improvement of tumor resection rate, i.e. R0 vs. R1 resection when intraoperative ultrasound evaluation of tissue margins is used during breast-conserving surgery (BCS). Patients and Methods: A total of 250 cases were evaluated retrospectively. The impact of ultrasound analysis onto clean margin rates was evaluated. A subgroup analysis assessed histology, stage, and neoadjuvant therapy with respect to R0 resection rate and ultrasound evaluation. Results: Of 250 BCS cases 84, (33.6%) underwent intraoperative ultrasound and 166 (66.4%) did not. Clean primary surgical margins (R0) were demonstrated for 218 (87.2%) patients after histological analysis. R0 resection was achieved in 81 (96.4%) patients in the ultrasound group compared to 137 (82.5%) in the control group. The difference between the two groups is significant. Conclusion: This study revealed a significant increase in R0 resection rates when intraoperative ultrasound was used to evaluate surgical margins.